منابع مشابه
Progression of Liver Diseases
To date, the knowledge on the natural history of HCV infection and the risk factors associated with progression of liver disease in children is limited. Progressive liver disease, including hepatocellular carcinoma, is rare but has been reported (1). Early effective treatment can prevent potential hepatic complications in later life. The association of Peg-IFN plus ribavirin is the option of ch...
متن کاملHypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases.
Angiogenesis is a dynamic, hypoxia-stimulated and growth factor-dependent process, and is currently referred to as the formation of new vessels from pre-existing blood vessels. Experimental and clinical studies have unequivocally reported that hepatic angiogenesis, irrespective of aetiology, occurs in conditions of chronic liver diseases (CLDs) characterized by perpetuation of cell injury and d...
متن کاملTexture Classification of Diffused Liver Diseases Using Wavelet Transforms
Introduction: A major problem facing the patients with chronic liver diseases is the diagnostic procedure. The conventional diagnostic method depends mainly on needle biopsy which is an invasive method. There are some approaches to develop a reliable noninvasive method of evaluating histological changes in sonograms. The main characteristic used to distinguish between the normal...
متن کاملImpact of insulin resistance on the progression of chronic liver diseases.
Recent studies have revealed a close relationship between insulin resistance (IR) and the progression of chronic liver diseases, although relatively little is known regarding the possible mechanisms involved. The aim of this study was to elucidate the impact of IR on the development of liver fibrosis and hepatocarcinogenesis using obese diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. L...
متن کاملModulation of TGF-beta signaling during progression of chronic liver diseases.
A large body of work has established roles for epithelial cells as important mediators of progressive fibrosis and carcinogenesis. Transforming growth factor-beta (TGF-beta) and pro-inflammatory cytokines are important inducers of fibro-carcinogenesis. TGF-beta signaling involves phosphorylation of Smad3 at middle linker and/or C-terminal regions. Reversible shifting of Smad3-dependent signalin...
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عنوان ژورنال:
hepatitis monthlyجلد ۱۲، شماره ۶، صفحات ۴۱۵-۴۱۶
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